The probiotic manufacturer from Italy has created a blend of L. plantarum-PBS067, L. rhamnosus-LRH020, and B.lactis-BL050 bacterial strains known for their antimicrobial activity against urogenital infections and bacterial vaginosis. These strains also help restore the vaginal microbiota.
Studies have shown that this blend can increase the relative abundance of Lactobacillus to reduce inflammation and reverse dysbiosis commonly seen in women’s health conditions like menopause.
An expert judging panel recognized the product for its clear market positioning and strong scientific evidence backing its claims.
Silvia Castegnara, the product manager at SynBalance Probiotics, mentioned that winning the award validates the importance of microbiome modulation in women’s health.
Restoring vaginal microbiota
Menopause leads to a decline in estrogen and progesterone levels, increasing the occurrence of genital symptoms. Estrogen is vital for glycogen production, which provides nutrients for lactobacilli growth, helping to maintain vaginal homeostasis. A decrease in lactobacilli due to estrogen decline can lead to an increase in pathogenic species and a rise in vaginal pH.
Research by SynBalance demonstrated that their product Femme was effective in preventing bacterial vaginosis recurrences, restoring a balanced microbiota, and promoting the growth of beneficial lactobacilli.
The probiotics facilitate the formation of a probiotic monolayer and acidic microenvironment, preventing pathogen adhesion and inhibiting pathogen cell growth by co-aggregating with G. vaginalis, E. coli, and C. albicans.
Castegnara highlighted the importance of addressing menopausal women and a recent clinical trial showed significant improvements in vaginal health with Femme supplementation.
SynBalance aims to focus on women’s health beyond medication to maintain a healthy balance of vaginal microbiota and achieve long-lasting positive effects.