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AHPA Updates 10 Entries to Online Botanical Safety Handbook

The American Herbal Products Association (AHPA) has released updates to 10 botanicals via the online Botanical Safety Handbook 2nd ed.

The following online entries have been updated:

• Bauhinia forficata (false indigo): The latest review identified a clinical trial, and animal and in vitro pharmacology studies.

• Benincasa hispida (winter melon rind): A literature review conducted in November 2022 did not identify any new relevant safety information for winter melon.

• Benincasa hispida (winter melon seed): A recent review added a reference relevant to safety during pregnancy.

• Cephaelis ipecacuanha (ipecac): A literature search provided updated references for U.S. FDA and pediatric medicine association recommendations and added references for the established effects of this herb.

• Chamaelirium luteum (false unicorn):  The most recent review identified additional references of historical uses of false unicorn.

• Corylus spp. (hazel): A recent review identified additional allergenicity studies (for nuts and pollen).

• Morinda citrifolia (noni):A literature review identified new references for an interactions case report, adverse events in clinical trials and case reports, human and animal pharmacology studies, and toxicity studies of various durations.

• Myrcia spp. (pedra hume): A review identified new studies for human and animal pharmacology and a cytotoxicity study. It also added additional Myrcia species to the entry.

• Myristica fragrans (mace, nutmeg): The recent review added references for adverse events, animal and in vitro pharmacology, and toxicity studies.

• Myroxylon spp. (tolu balsam tree): A literature review identified additional references for case reports and allergic reactions.

AHPA members can obtain a hard copy or an annual individual subscription to the online Botanical Safety Handbook for $95, with multi-user rates available for companies needing expanded access. Information about hard copy purchases and subscriptions can be found on the AHPA website.

Subscribers to the online Botanical Safety Handbook can review short descriptions of updated entries in the “Revisions” panel on the online version homepage when they log in. The online Botanical Safety Handbook is undergoing review of existing entries and the addition of new entries to provide the latest safety information before it can be included in the next print edition of the handbook. AHPA will continue to post additional updates to existing entries as well as develop new botanical entries. Current subscribers are notified of these updates when they become available.

AHPA’s Botanical Safety Handbook is an essential tool for anyone who manufactures, recommends or uses herbal products, the association stated. The handbook provides safety information on over 500 species of herbs, derived from data compiled from clinical trials, pharmacological and toxicological studies, medical case reports, and historical texts. All entries are reviewed by an Expert Advisory Council that includes some of the most renowned herbal and integrative medicine experts in the United States.

For more information, visit www.ahpa.org.

The American Herbal Products Association (AHPA) has released updates to 10 botanicals via the online Botanical Safety Handbook 2nd ed.

The following online entries have been updated:

• Bauhinia forficata (false indigo): The latest review identified a clinical trial, and animal and in vitro pharmacology studies.

• Benincasa hispida (winter melon rind): A literature review conducted in November 2022 did not identify any new relevant safety information for winter melon.

• Benincasa hispida (winter melon seed): A recent review added a reference relevant to safety during pregnancy.

• Cephaelis ipecacuanha (ipecac): A literature search provided updated references for U.S. FDA and pediatric medicine association recommendations and added references for the established effects of this herb.

• Chamaelirium luteum (false unicorn):  The most recent review identified additional references of historical uses of false unicorn.

• Corylus spp. (hazel): A recent review identified additional allergenicity studies (for nuts and pollen).

• Morinda citrifolia (noni):A literature review identified new references for an interactions case report, adverse events in clinical trials and case reports, human and animal pharmacology studies, and toxicity studies of various durations.

• Myrcia spp. (pedra hume): A review identified new studies for human and animal pharmacology and a cytotoxicity study. It also added additional Myrcia species to the entry.

• Myristica fragrans (mace, nutmeg): The recent review added references for adverse events, animal and in vitro pharmacology, and toxicity studies.

• Myroxylon spp. (tolu balsam tree): A literature review identified additional references for case reports and allergic reactions.

AHPA members can obtain a hard copy or an annual individual subscription to the online Botanical Safety Handbook for $95, with multi-user rates available for companies needing expanded access. Information about hard copy purchases and subscriptions can be found on the AHPA website.

Subscribers to the online Botanical Safety Handbook can review short descriptions of updated entries in the “Revisions” panel on the online version homepage when they log in. The online Botanical Safety Handbook is undergoing review of existing entries and the addition of new entries to provide the latest safety information before it can be included in the next print edition of the handbook. AHPA will continue to post additional updates to existing entries as well as develop new botanical entries. Current subscribers are notified of these updates when they become available.

AHPA’s Botanical Safety Handbook is an essential tool for anyone who manufactures, recommends or uses herbal products, the association stated. The handbook provides safety information on over 500 species of herbs, derived from data compiled from clinical trials, pharmacological and toxicological studies, medical case reports, and historical texts. All entries are reviewed by an Expert Advisory Council that includes some of the most renowned herbal and integrative medicine experts in the United States.


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